特邀讲座——用于无创个人健康监测的实用可穿戴电子平台

Invited Lecture - Integrated Wearable Microgrids for Autonomous Energy Management and Biosensing


讲座简介:


用于非侵入式个人健康监测的实用可穿戴电子平台需要先进的传感模式和高度集成的电子系统。然而,由于能量供应不足、传感系统能力有限、用户体验问题、复杂的电路调节以及设备尺寸较大,这些系统在长期连续健康监测方面面临诸多限制。通过应用可穿戴微电网设计理念,我们提出了一种可穿戴、无线、能量自主的多路汗液检测系统,该系统可在指尖上运行。该系统利用高效、自我电压调节的可穿戴微电网,由酶生物燃料电池(BFCs)和氯化银-锌(AgCl-Zn)电池组成,从自然出汗中获取并储存能量,无需任何身体运动或体力消耗。关键的设计考量包括精准的能量预算、兼容的电路调节以及针对特定场景的互补特性,这些都被用于无缝创建能量微电网,并将其与传感器阵列和微控制器集成至单个指尖。该传感模式结合了渗透泵和纸基流体系统,能够持续将指尖自然汗液输送到传感器阵列,以实现按需的多代谢物检测。通过低功耗电子设备进行信号采集和无线数据传输,该系统可以完全依靠自然指尖汗液供电,持续检测葡萄糖、抗坏血酸、乳酸和左旋多巴水平。这种集成在指尖的汗液监测系统为轻松、可靠、且自我可持续的综合非侵入式代谢监测提供了一种解决方案。


主讲人:丁士超 


主讲人简介:


丁士超博士目前是加州大学圣地亚哥分校(UCSD)纳米工程系的博士后学者,与著名教授Joseph Wang合作。他于2022年在华盛顿州立大学(WSU)获得博士学位,导师为林岳和教授。他的研究领域主要集中在基于功能性纳米材料(特别是单原子催化剂和类酶)的电催化和类酶催化、生物传感以及可穿戴电子设备和微电网等方面。截至目前,丁博士已发表78篇学术论文,其中34篇为第一作者、共同第一作者或通讯作者。这些论文发表在《Nature Medicine》、《Nature Electronics》、《Nature Reviews Materials》、《Nature Reviews Endocrinology》、《Advanced Materials》、《Advanced Energy Materials》等国际顶尖期刊上。他的论文被引用次数超过3300次,Google Scholar显示其H指数为31。此外,丁博士还担任多家学术期刊的编辑委员会成员或青年编辑,包括《Bioengineering》、《The Innovation》、《Advanced Powder Materials》、《Exploration》、《VIEW》、《Soft Science》、《Med-X》等。他也是100多种期刊的同行评审员,包括《Nature Synthesis》、《Nature Communications》等,累计完成审稿约400次。


讲座时间:11月16日 13:30


讲座地点:复旦大学江湾校区教学楼JA105



Lecture Bio:


Practical wearable electronics platforms for non-invasive personal health monitoring require advanced sensing modalities and highly integrated electronic systems. However, these systems face limitations in long-term continuous healthcare monitoring due to inadequate energy supply, limited sensing system capabilities, user experience issues, complex circuitry regulation, and large device dimensions. By applying the wearable microgrid design concept, we present a wearable, wireless, energy-autonomous, multiplexed sweat sensing system that operates on the fingertip. This system utilizes a high-efficiency, self-voltage-regulated wearable microgrid, composed of enzymatic biofuel cells (BFCs) and silver chloride-zinc (AgCl-Zn) batteries, to harvest and store energy from natural perspiration without requiring any body movement or physical exertion. Critical design considerations, including accurate energy budgeting, compatible circuit regulation, and scenario-specific complementary characteristics, were employed to seamlessly create the energy microgrid and integrate it with the sensor array and microcontroller onto a single fingertip. The sensing modality combines an osmotic pump and paper fluidic system to continuously deliver natural fingertip perspiration to a sensor array for on-demand multi-metabolite sensing. Coupled with low-power electronics for signal acquisition and wireless data transmission, the system can be solely powered by natural fingertip perspiration while detecting glucose, ascorbate, lactate, and levodopa levels over extended periods. The integrated sweat monitoring system on the fingertip provides a solution for effortless, reliable, and self-sustainable comprehensive non-invasive metabolic monitoring.


Lecturer:


Dr. Shichao Ding


Lecturer Bio:


Dr. Shichao Ding is currently a postdoctoral scholar at University of California San Diego and worked with distinguished professor Joseph Wang. He received his Ph.D. degree from Washington State University (PI: Prof. Yuehe Lin) in 2022, respectively. His research focuses on functional nanomaterials-based (especially single-atom catalyst/nanozyme) electrocatalysis and enzyme-like catalysis, biosensing, and wearable electronics/microgrid. He has published 78 papers (34 papers as first/co-first or corresponding authors), including Nature Medicine, Nature Electronics, Nature Review Materials, Nature Review Endocrinology, Advanced Materials, Advanced Energy Materials, etc. His papers have been cited more than >3,300 times with an H index of 31 (Google Scholar). Dr. Ding currently serves as the Editorial board member of Bioengineering, Youth/Junior editors of The Innovation, Advanced Powder Materials, Exploration, VIEW, Soft Science, Med-X, etc, and Peer reviewers for 100 journals, including Nature Synthesis, Nature Communications, etc, for reviewing a total of 400 times.


Lecture Time:


November 16, 1:30 PM


Location:


Classroom JA105, Jiangwan Campus, Fudan University